METHODOLOGY FOR EXISTING RAILWAY RECONSTRUCTION WITH CONSTRAINED OPTIMIZATION BASED ON POINT CLOUD DATA

The reconstruction of an existing railway is important for railway reformation or double-track design.Obtaining the curve parameters of the railway and the location of the main stake accurately and rapidly is the key issue for existing railway reconstruction.A new method based on point cloud data is proposed in this paper.The issue of reconstructio

B lymphocytes play critical roles in the development of autoimmunity, acting as autoantibody manufacturers, antigen-presenting cells, and producers of cytokines.Pan-B cell depletion has demonstrated efficacy in treatment of many autoimmune disorders, but carries with it an unfavorable safety profile due to orange zinger tomato global immune suppres